Publication (since 2016/2) 

Original articles

  1. Murata Y, Ikegame T, Koike S, Saito T, Ikeda M, Sasaki T, Iwata N, Kasai K, Bundo M*, Iwamoto K*. Global DNA hypomethylation and its correlation to the betaine level in peripheral blood of patients with schizophrenia.
    Progress in Neuropsychopharmacology & Biological Psychiatry, in press

  2. Zhao Z, Jinde S*, Koike S, Tada M, Satomura Y, Yoshikawa A, Nishimura Y, Takizawa R, Kinoshita A, Sakakibara E, Sakurada H, Yamagishi M, Nishimura F, Inai A, Nishioka M, Eriguchi Y, Araki T, Takaya A, Kan C, Umeda M, Shimazu A, Hashimoto H, Bundo M, Iwamoto K, Kakiuchi C, Kasai K. Altered expression of microRNA-223 in the plasma of patients with first-episode schizophrenia and its possible relation to neuronal migration-related genes.
    Translational Psychiatry, 9:289, 2019.

  3. Ide M†, Ohnishi T†, Toyoshima M, Balan S, Maekawa M, Shimamoto-Mitsuyama C, Iwayama Y, Ohba H, Watanabe A, Ishii T, Shibuya N, Kimura Y, Hisano Y, Murata Y, Hara T, Morikawa M, Hashimoto K, Nozaki Y, Toyota T, Wada Y, Tanaka Y, Kato T, Nishi A, Fujisawa S, Okano H, Itokawa M, Hirokawa N, Kunii Y, Kakita A, Yabe H, Iwamoto K, Meno K, Katagiri T, Dean B, Uchida K, Kimura H, Yoshikawa T*. Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology.
    EMBO Molecular Medicine, e10695, 2019.

  4. Murata Y†, Fujii A†, Kanata S, Fujikawa S, Ikegame T, Nakachi Y, Zhao Z, Jinde S, Kasai K, Bundo M*, Iwamoto K*. Evaluation of the usefulness of saliva for DNA methylation analysis in cohort studies.
    Neuropsychopharmacology Reports, in press

  5. Okada N, Ando S, Sanada M, Hirata‐Mogi S, Iijima Y,  Sugiyama H, Shirakawa T, Yamagishi M, Kanehara A, Morita M, Yagi T, Hayashi N, Koshiyama D, Morita K, Sawada K, Ikegame T, Sugimoto N, Toriyama R, Masaoka M, Fujikawa S, Kanata S, Tada M, Kirihara K, Yahata N, Araki T, Jinde S, Kano Y, Koike S, Endo K, Yamasaki S, Nishida A, Hiraiwa‐Hasegawa M, Bundo M, Iwamoto K, Tanaka SC, Kasai K*. The population‐neuroscience study of the Tokyo TEEN Cohort (pn‐TTC): a cohort longitudinal study to explore the neurobiological substrates of adolescent psychological and behavioral development.
    Psychiatry and Clinical Neurosciences, 73:231-242, 2019

  6. Murata Y, Bundo M*, Sunaga F, Kasai K, Iwamoto K*.DNA methylation profiling in a neuroblastoma cell line exposed to the antipsychotic perospirone.
    Pharmacopsychiatry, 52:63-69, 2019

  7. Nishioka M, Bundo M, Ueda J, Yoshikawa A, Nishimura F, Sasaki T, Kakiuchi C, Kasai K, Kato T*, Iwamoto K*. Identification of somatic mutations in monozygotic twins discordant for psychiatric disorders.
    npj Schizophrenia, 4:7, 2018

  8. Miura I*, Kunii Y, Hino M, Hoshino H, Matsumoto K, Kanno-Nozaki K, Horikoshi S, Kaneko H, Bundo M, Iwamoto K, Yabe H.
    DNA methylation of ANKK1 and response to aripiprazole in patients with acute schizophrenia: A preliminary study.
    Journal of Psychiatric Research, 100:84-87, 2018

  9. Sugawara H, Murata Y, Ikegame T, Sawamura R, Shimanaga S, Takeoka Y, Saito T, Ikeda M, Yoshikawa A, Nishimura F, Kawamura Y, Kakiuchi C, Sasaki T, Iwata N, Hashimoto M, Kasai K, Kato T, Bundo M*, Iwamoto K*.
    DNA methylation analyses of the candidate genes identified by a methylome-wide association study revealed common epigenetic alterations in schizophrenia and bipolar disorder.

    Psychiatry and Clinical Neurosciences, 72:245-254, 2018

  10. Shimada-Sugimoto M, Otowa T*, Miyagawa T, Umekage T, Kawamura Y, Bundo M, Iwamoto K, Ikegame T, Tochigi M, Kasai K, Kaiya H, Tanii H, Okazaki Y, Tokunaga K, Sasaki T.
    An epigenome-wide methylation study of healthy individuals with or without depressive symptoms.
    Journal of Human Genetics​, 63:319-326, 2018

  11. Nishioka M, Bundo M, Ueda J, Katsuoka F, Sato Y, Kuroki Y, Ishii T, Ukai W, Murayama S, Hashimoto E, Nagasaki M, Yasuda J, Kasai K, Kato T*, Iwamoto K​*.
    Identification of somatic mutations in postmortem human brains by whole genome sequencing and their implications for psychiatric disorders.
    Psychiatry and Clinical Neurosciences, 72:280-294, 2018

  12. Yoshikawa A, Nishimura F, Inai, A, Eriguchi, Y, Nishioka, M, Takaya A, Tochigi M, Kawamura Y, Umekage T, Kato K, Sasaki T, Ohashi Y, Iwamoto K, Kasai K, Kakiuchi C*.
    Mutations of the glycine cleavage system genes possibly affect the negative symptoms of schizophrenia through metabolomic profile changes.
    Psychiatry and Clinical Neurosciences, 72:168-179, 2018

  13. Murata Y, Bundo M, Ueda J, Kubota-Sakashita M, Kasai K, Kato T, Iwamoto K*.
    DNA methylation and hydroxymethylation analyses of the active LINE-1 subfamilies in mice.
    Scientific Reports, 7:13624, 2017

  14. Maekawa M, Watanabe A, Iwayama Y, Kimura T, Hamazaki K, Balan S, Ohba H, Hisano Y, Nozaki Y, Ohnishi T, Toyoshima M, Shimamoto C, Iwamoto K, Bundo M, Osumi N, Takahashi E, Takashima A, Yoshikawa T*.
    Polyunsaturated fatty acid deficiency during neurodevelopment in mice models the prodromal state of schizophrenia through epigenetic changes in nuclear receptor genes.
    Translational Psychiatry, 7:e1229, 2017

  15. Ueda J†, Murata Y†, Bundo M, Oh-Nishi A, Kassai H, Ikegame T, Zhao Z, Jinde S, Aiba A, Suhara T, Kasai K, Kato T, Iwamoto K*. († equal contribution)
    Use of human methylation arrays for epigenome research in the common marmoset (Callithrix jacchus).
    Neuroscience Research, 120:60-65, 2017

  16. Shimada-Sugimoto M, Otowa T*, Miyagawa T, Umekage T, Kawamura Y, Bundo M, Iwamoto K, Tochigi M, Kasai K, Kaiya H, Tanii H, Okazaki Y, Tokunaga K, Sasaki T.
    Epigenome-wide association study of DNA methylation in panic disorder.
    Clinical Epigenetics, 9:6, 2017

  17. Kasahara T, Ishiwata M, Kakiuchi C, Fuke S, Iwata N, Ozaki N, Kunugi H, Minabe Y, Nakamura K, Iwata Y, Fujii K, Kanba S, Ujike H, Kusumi I, Kataoka M, Matoba N, Takata A, Iwamoto K, Yoshikawa T, Kato T*.
    Enrichment of deleterious variants of mitochondrial DNA polymerase gene (POLG1) in bipolar disorder.
    Psychiatry and Clinical Neurosciences, 71:518-529, 2017

Reviews

  1. Nishioka M, Bundo M, Iwamoto K*, Kato T*. 
    Somatic mutations in the human brain: implications for psychiatric research.
    Molecular Psychiatry, 24:839-856, 2019

  2. Iwamoto K*. 
    Understanding the epigenetic architecture of psychiatric disorders: modifications and beyond.

    Psychiatry and Clinical Neurosciences, 72:194, 2018

  3. Bundo M*, Kato T, Iwamoto K.
    Estimation of LINE-1 Copy Number in the Brain Tissue and Isolated Neuronal Nuclei.
    In: Frade J., Gage F. (eds) Genomic Mosaicism in Neurons and Other Cell Types. 
    Neuromethods, 2017 vol 131. Humana Press, New York, NY