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Department of Molecular Brain Science

Kumamoto University, Japan

We study the etiology and pathophysiology of psychiatric disorders such as schizophrenia, bipolar disorder, and major depression. Based on basic research, we develop the methods for early diagnosis and treatment. 

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Entrance examination for Graduate School

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Kumamoto University


Research Highlights


Bundo M, Ueda J, et al.,
Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder.
Molecular Psychiatry in press


Ikegame T, Hidaka Y et al., 
Identification and functional characterization of the extremely long allele of the serotonin transporter-linked polymorphic region. 
Translational Psychiatry, 11:119, 2021


Ikegame T, Bundo M et al.,
Promoter activity-based case-control association study on SLC6A4 highlighting hypermethylation and altered amygdala volume in male patients with schizophrenia.
Schizophrenia Bulletin, 46:1577-1586, 2020

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